Assay Detail
Functional
CHEMBL853865
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Cytotoxicity against human LnCaP cell line by MTT assay after 72 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Novel Schiff base copper complexes of quinoline-2 carboxaldehyde as proteasome inhibitors in human prostate cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.67 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL215065 | — | — | 1 | 4.80 |
| CHEMBL385902 | — | — | 1 | 4.70 |
| CHEMBL1162934 | — | — | 1 | 4.51 |
| CHEMBL215187 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL215065 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL385902 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL1162934 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL215187 | — | IC50 | - | — | - |