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Assay Detail

CHEMBL855086

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rabbit liver guanase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Guanine deaminase (CHEMBL3129)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design of inhibitors against guanase: synthesis and biochemical evaluation of analogues of azepinomycin.
Ujjinamatada RK, Bhan A, Hosmane RS.
Bioorg Med Chem Lett (2006) 16 : 5551 -5554
PubMed 16920357 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 4.49 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL374469 1 4.70
CHEMBL220699 1 4.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL374469 Ki = 20100.0 nM 4.70
CHEMBL220699 Ki = 53600.0 nM 4.27