Assay Detail
Functional
CHEMBL855199
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antioxidant activity assessed as inhibition of rat liver microsomal lipid peroxidation
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Subcellular | Microsome |
| Confidence | 2 — Organism |
| Curated By | Autocuration |
Publication
Structures, biogenesis, and biological activities of pyrano[4,3-c]isochromen-4-one derivatives from the Fungus Phellinus igniarius.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.26 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL221760 | PHELLIGRIDIN I | — | 1 | 5.43 |
| CHEMBL376755 | PHELLIGRIDIN H | — | 1 | 5.32 |
| CHEMBL373529 | PHELLIGRIDIN J | — | 1 | 5.19 |
| CHEMBL205945 | DAVALLIALACTONE | — | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL221760 | PHELLIGRIDIN I | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL376755 | PHELLIGRIDIN H | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL373529 | PHELLIGRIDIN J | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL205945 | DAVALLIALACTONE | IC50 | = | 8200.0 | nM | 5.09 |