Assay Detail
ADMET
CHEMBL855200
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Cytotoxicity against human A2708 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | A2708 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structures, biogenesis, and biological activities of pyrano[4,3-c]isochromen-4-one derivatives from the Fungus Phellinus igniarius.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.53 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL84 | TOPOTECAN | 4.0 | 1 | 5.92 |
| CHEMBL373529 | PHELLIGRIDIN J | — | 1 | 5.14 |
| CHEMBL376755 | PHELLIGRIDIN H | — | 1 | - |
| CHEMBL205945 | DAVALLIALACTONE | — | 1 | - |
| CHEMBL221760 | PHELLIGRIDIN I | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL84 | TOPOTECAN | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL373529 | PHELLIGRIDIN J | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL376755 | PHELLIGRIDIN H | IC50 | > | 10.0 | ug.mL-1 | - |
| CHEMBL205945 | DAVALLIALACTONE | IC50 | > | 10.0 | ug.mL-1 | - |
| CHEMBL221760 | PHELLIGRIDIN I | IC50 | > | 10.0 | ug.mL-1 | - |