Assay Detail
Functional
CHEMBL855403
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Antiviral activity against Vaccinia virus WR infected HFF cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vaccinia virus |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.74 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1257073 | TECOVIRIMAT | 4.0 | 1 | 7.00 |
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1257073 | TECOVIRIMAT | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5314375 | CIDOFOVIR | EC50 | = | 33000.0 | nM | 4.48 |