Assay Detail
Functional
CHEMBL856040
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Inhibitory concentration against epstein-barr virus (EBV) infected H-1 cells was determined
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.23 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305612 | — | — | 1 | 6.70 |
| CHEMBL306257 | SYNGUANOL | — | 1 | 6.52 |
| CHEMBL75950 | — | — | 1 | 6.16 |
| CHEMBL74478 | — | — | 1 | 5.52 |
| CHEMBL75956 | — | — | 1 | - |
| CHEMBL76121 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305612 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL306257 | SYNGUANOL | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL75950 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL74478 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL75956 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL76121 | — | IC50 | > | 10000.0 | nM | - |