Assay Detail
Binding
CHEMBL856086
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was evaluated for the inhibition human of Butyrylcholinesterase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.40 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13122 | — | — | 1 | 7.60 |
| CHEMBL94 | PHYSOSTIGMINE | 3.0 | 1 | 7.46 |
| CHEMBL418712 | — | — | 1 | 6.00 |
| CHEMBL13206 | — | — | 1 | 5.89 |
| CHEMBL13426 | — | — | 1 | 5.72 |
| CHEMBL418714 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13122 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL94 | PHYSOSTIGMINE | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL418712 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL13206 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL13426 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL418714 | — | IC50 | = | 1900.0 | nM | 5.72 |