Assay Detail
Binding
CHEMBL856202
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Ability to inhibit Prostaglandin G/H synthase in guinea pig
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Phenylephrine derivatives as leukotriene D4 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.82 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8747 | REV-5901 | — | 1 | 5.28 |
| CHEMBL162358 | TOMELUKAST | 2.0 | 1 | 4.36 |
| CHEMBL2115108 | — | — | 1 | - |
| CHEMBL417968 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8747 | REV-5901 | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL162358 | TOMELUKAST | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL2115108 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL417968 | — | IC50 | > | 100000.0 | nM | - |