Assay Detail
Binding
CHEMBL856210
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Compound was evaluated for inhibitory activity against HIV-2 protease
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 2 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The development of cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.46 | 9.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17612 | — | — | 1 | 9.62 |
| CHEMBL114 | SAQUINAVIR | 4.0 | 1 | 9.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17612 | — | IC50 | = | 0.24 | nM | 9.62 |
| CHEMBL114 | SAQUINAVIR | IC50 | = | 0.5 | nM | 9.30 |