Assay Detail
Functional
CHEMBL856255
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to inhibit PGD-2 induced change in the shape of human eosinophils expressing CRTH2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.59 | 7.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL196707 | — | — | 1 | 7.13 |
| CHEMBL199040 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL196707 | — | IC50 | = | 74.0 | nM | 7.13 |
| CHEMBL199040 | — | IC50 | = | 908.0 | nM | 6.04 |