Assay Detail

CHEMBL857034

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Functional

pA2 value for Angiotensin II receptor

ChEMBL ↗

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Target

Type-1 angiotensin II receptor A (CHEMBL329) ↗

Open DB target context

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Type-1 angiotensin II receptor A (CHEMBL329) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Type-1 angiotensin II receptor A

CHEMBL329

Anchored from Assay target.

Protein identity Type-1 angiotensin II receptor A

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Confidence	8 — Homologous single protein target
Curated By	Autocuration

Target

Type-1 angiotensin II receptor A (CHEMBL329) ↗

Type	SINGLE PROTEIN
Organism	Rattus norvegicus

Publication

Conformational restriction of angiotensin II: cyclic analogues having high potency.

Spear KL, Brown MS, Reinhard EJ, McMahon EG, Olins GM, Palomo MA, Patton DR.
J Med Chem (1990) 33 : 1935 -1940
PubMed 2362273 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	9.09	9.09

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2373017	—	—	1	9.09

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2373017	—	Kd	=	0.8128	nM	9.09