Assay Detail
Functional
CHEMBL857154
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vivo pA2 value represent the negative logarithm of the anti-vasopressor effective dose divided by the estimated volume of distribution (67 mL/kg).
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design of more potent antagonists of the antidiuretic responses to arginine-vasopressin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.10 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2370969 | — | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2370969 | — | Kd | = | 7.943 | nM | 8.10 |