Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL857175

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against mouse Histone deacetylase 1 (HDAC1)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Histone deacetylase 1 (CHEMBL4001)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors.
Wang DF, Wiest O, Helquist P, Lan-Hargest HY, Wiech NL.
J Med Chem (2004) 47 : 3409 -3417
PubMed 15189037 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.29 6.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL12760 1 6.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL12760 IC50 = 512.86 nM 6.29