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Assay Detail

CHEMBL857508

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The apparent binding affinity against cathepsin L.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Procathepsin L (CHEMBL3837)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Protease inhibitors: current status and future prospects.
Leung D, Abbenante G, Fairlie DP.
J Med Chem (2000) 43 : 305 -341
PubMed 10669559 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 6.32 6.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL281540 1 6.47
CHEMBL57836 1 6.16
CHEMBL113805 1 -
CHEMBL113724 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL281540 Ki = 340.0 nM 6.47
CHEMBL57836 Ki = 700.0 nM 6.16
CHEMBL113805 Ki > 1000.0 nM -
CHEMBL113724 Ki > 1000.0 nM -