Assay Detail
Binding
CHEMBL857517
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Compound was measured for the apparent inhibition constant at pepsin
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New pepstatin analogues: synthesis and pepsin inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 9.67 | 10.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL74043 | — | — | 1 | 10.75 |
| CHEMBL73985 | — | — | 1 | 10.40 |
| CHEMBL75248 | — | — | 1 | 9.46 |
| CHEMBL306067 | — | — | 1 | 8.95 |
| CHEMBL74149 | — | — | 1 | 8.81 |
| CHEMBL296588 | PEPSTATIN | 2.0 | 1 | - |
| CHEMBL74075 | — | — | 1 | - |
| CHEMBL72563 | — | — | 1 | - |
| CHEMBL72555 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL74043 | — | Ki | = | 0.0177 | nM | 10.75 |
| CHEMBL73985 | — | Ki | = | 0.0394 | nM | 10.40 |
| CHEMBL75248 | — | Ki | = | 0.346 | nM | 9.46 |
| CHEMBL306067 | — | Ki | = | 1.13 | nM | 8.95 |
| CHEMBL74149 | — | Ki | = | 1.54 | nM | 8.81 |
| CHEMBL296588 | PEPSTATIN | Ki | = | 4.6e-08 | nM | - |
| CHEMBL74075 | — | Ki | = | 0.00019 | nM | - |
| CHEMBL72563 | — | Ki | = | 0.00041 | nM | - |
| CHEMBL72555 | — | Ki | = | 3.1e-06 | nM | - |