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Assay Detail

CHEMBL857603

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Binding
Dissociation constant against protein tyrosine phosphatase PTB1B receptor was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.
Liu G, Xin Z, Pei Z, Hajduk PJ, Abad-Zapatero C, Hutchins CW, Zhao H, Lubben TH, Ballaron SJ, Haasch DL, Kaszubska W, Rondinone CM, Trevillyan JM, Jirousek MR.
J Med Chem (2003) 46 : 4232 -4235
PubMed 13678400 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 2.92 2.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1169 AMINOSALICYLIC ACID 4.0 1 2.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1169 AMINOSALICYLIC ACID Kd = 1200000.0 nM 2.92