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Assay Detail

CHEMBL857670

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration of EGFr
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Epidermal growth factor receptor (CHEMBL203)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as potent Src kinase inhibitors.
Berger DM, Dutia M, Birnberg G, Powell D, Boschelli DH, Wang YD, Ravi M, Yaczko D, Golas J, Lucas J, Boschelli F.
J Med Chem (2005) 48 : 5909 -5920
PubMed 16161995 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.57 5.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL195029 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL195029 IC50 = 2700.0 nM 5.57