Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL857773

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro antagonistic potency against Angiotensin II receptor, type 1 in rat liver
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Tissue Liver
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Angiotensin II receptor (AT-1) type-1 (CHEMBL2094250)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
Wexler RR, Greenlee WJ, Irvin JD, Goldberg MR, Prendergast K, Smith RD, Timmermans PB.
J Med Chem (1996) 39 : 625 -656
PubMed 8576904 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL352257 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL352257 Ki = 1.995 nM 8.70