Assay Detail
Binding
CHEMBL858800
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Binding affinity to 5HT2 receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.21 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1729 | CISAPRIDE | 4.0 | 1 | 8.21 |
| CHEMBL34291 | — | — | 1 | - |
| CHEMBL383577 | — | — | 1 | - |
| CHEMBL201878 | — | — | 1 | - |
| CHEMBL201946 | — | — | 1 | - |
| CHEMBL2448165 | — | — | 1 | - |
| CHEMBL202434 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1729 | CISAPRIDE | IC50 | = | 6.1 | nM | 8.21 |
| CHEMBL34291 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL383577 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL201878 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL201946 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2448165 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL202434 | — | IC50 | > | 10000.0 | nM | - |