Assay Detail
Binding
CHEMBL858936
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Binding affinity for Helicobacter pylori DHQase 2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Helicobacter pylori |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
3-dehydroquinate dehydratase (CHEMBL4680) ↗| Type | SINGLE PROTEIN |
| Organism | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) |
Publication
Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.15 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1261 | CITRIC ACID | 4.0 | 1 | 5.60 |
| CHEMBL202311 | — | — | 1 | 4.70 |
| CHEMBL190265 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1261 | CITRIC ACID | Kd | = | 2500.0 | nM | 5.60 |
| CHEMBL202311 | — | Kd | = | 20000.0 | nM | 4.70 |
| CHEMBL190265 | — | Kd | = | 370000.0 | nM | - |