Assay Detail
Binding
CHEMBL859282
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Inhibition of bovine alpha-L-fucosidase
7
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Asymmetric synthesis of the L-fuco-nojirimycin, a nanomolar alpha-L-fucosidase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.39 | 9.00 |
| IC50 | 1 | 8.30 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL203969 | — | — | 1 | 9.00 |
| CHEMBL383067 | — | — | 1 | 9.00 |
| CHEMBL314772 | DEOXYFUCONOJIRIMYCIN | — | 2 | 8.52 |
| CHEMBL203863 | — | — | 1 | 5.52 |
| CHEMBL203795 | — | — | 1 | 4.89 |
| CHEMBL203959 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL203969 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL383067 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL314772 | DEOXYFUCONOJIRIMYCIN | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL314772 | DEOXYFUCONOJIRIMYCIN | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL203863 | — | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL203795 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL203959 | — | Ki | = | 660000.0 | nM | - |