Assay Detail
Functional
CHEMBL859397
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 4 receptor in non-electrically stimulated guinea-pig ileum.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Design and synthesis of novel ligands for the 5-HT3 and the 5-HT4 receptor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.00 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL143197 | — | — | 1 | 6.30 |
| CHEMBL56564 | TROPISETRON | 3.0 | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL143197 | — | Kd | = | 501.19 | nM | 6.30 |
| CHEMBL56564 | TROPISETRON | Kd | = | 1995.26 | nM | 5.70 |