Assay Detail
Binding
CHEMBL859996
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]WAY-100635 from 5HT1A receptor in porcine striatal membrane
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Tissue | Striatum |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and biological investigations of dopaminergic partial agonists preferentially recognizing the D4 receptor subtype.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.80 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL379602 | — | — | 1 | 8.17 |
| CHEMBL378455 | — | — | 1 | 7.43 |
| CHEMBL240773 | QUINPIROLE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL379602 | — | Ki | = | 6.8 | nM | 8.17 |
| CHEMBL378455 | — | Ki | = | 37.0 | nM | 7.43 |
| CHEMBL240773 | QUINPIROLE | Ki | - | — | - |