Assay Detail
Binding
CHEMBL860505
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]SCH 23390 from D1 receptor of porcine striatal membrane
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Fancy bioisosteres: novel paracyclophane derivatives as super-affinity dopamine D3 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.07 | 6.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL210567 | — | — | 2 | 6.31 |
| CHEMBL426863 | — | — | 1 | 6.24 |
| CHEMBL25236 | BP-897 | — | 1 | 6.12 |
| CHEMBL208847 | — | — | 1 | 6.11 |
| CHEMBL209876 | — | — | 1 | 6.01 |
| CHEMBL210461 | — | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL210567 | — | Ki | = | 490.0 | nM | 6.31 |
| CHEMBL426863 | — | Ki | = | 570.0 | nM | 6.24 |
| CHEMBL210567 | — | Ki | = | 660.0 | nM | 6.18 |
| CHEMBL25236 | BP-897 | Ki | = | 760.0 | nM | 6.12 |
| CHEMBL208847 | — | Ki | = | 780.0 | nM | 6.11 |
| CHEMBL209876 | — | Ki | = | 970.0 | nM | 6.01 |
| CHEMBL210461 | — | Ki | = | 2800.0 | nM | 5.55 |