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Assay Detail

CHEMBL860743

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to canine CCK2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Canis lupus familiaris
Confidence 9 — Direct single protein target
Curated By Expert

Target

Gastrin/cholecystokinin type B receptor (CHEMBL5595)
Type SINGLE PROTEIN
Organism Canis lupus familiaris

Publication

Novel, achiral 1,3,4-benzotriazepine analogues of 1,4-benzodiazepine-based CCK(2) antagonists that display high selectivity over CCK(1) receptors.
McDonald IM, Austin C, Buck IM, Dunstone DJ, Griffin E, Harper EA, Hull RA, Kalindjian SB, Linney ID, Low CM, Pether MJ, Spencer J, Wright PT, Adatia T, Bashall A.
J Med Chem (2006) 49 : 2253 -2261
PubMed 16570921 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.91 7.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL205455 1 7.91

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL205455 Ki = 12.3 nM 7.91