Assay Detail
Functional
CHEMBL861269
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonism of OT-induced response at OT receptor in rat uterine strips
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.91 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL382301 | ATOSIBAN | 4.0 | 1 | 7.92 |
| CHEMBL201889 | — | — | 1 | 5.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL382301 | ATOSIBAN | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL201889 | — | IC50 | = | 1259.0 | nM | 5.90 |