Assay Detail
Binding
CHEMBL861972
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to beta amyloid in human corpse AD brain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.30 | 8.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93124 | PITTSBURGH COMPOUND B UNLABELLED | 2.0 | 1 | 8.37 |
| CHEMBL381642 | — | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93124 | PITTSBURGH COMPOUND B UNLABELLED | Ki | = | 4.3 | nM | 8.37 |
| CHEMBL381642 | — | Ki | = | 6.0 | nM | 8.22 |