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Assay Detail

CHEMBL862184

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PP1
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Protein tyrosine phosphatase 1B inhibitors from Morus root bark.
Cui L, Na M, Oh H, Bae EY, Jeong DG, Ryu SE, Kim S, Kim BY, Oh WK, Ahn JS.
Bioorg Med Chem Lett (2006) 16 : 1426 -1429
PubMed 16356713 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 4.75 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL382338 SANGGENON G 1 4.75
CHEMBL204813 SANGGENON C 1 -
CHEMBL426373 1 -
CHEMBL561971 MORACIN P 1 -
CHEMBL205924 MORACIN O 1 -
CHEMBL377937 KUWANON L 1 -
CHEMBL378806 MULBERROFURAN C 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL382338 SANGGENON G IC50 = 17800.0 nM 4.75
CHEMBL204813 SANGGENON C IC50 > 80000.0 nM -
CHEMBL426373 IC50 - -
CHEMBL561971 MORACIN P IC50 > 80000.0 nM -
CHEMBL205924 MORACIN O IC50 > 80000.0 nM -
CHEMBL377937 KUWANON L IC50 > 80000.0 nM -
CHEMBL378806 MULBERROFURAN C IC50 > 50000.0 nM -