Assay Detail
Binding
CHEMBL862519
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to MMP9
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Conversion of potent MMP inhibitors into selective TACE inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.33 | 7.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL100570 | — | — | 1 | 7.33 |
| CHEMBL204495 | — | — | 1 | - |
| CHEMBL203972 | — | — | 1 | - |
| CHEMBL379469 | — | — | 1 | - |
| CHEMBL203160 | — | — | 1 | - |
| CHEMBL204549 | — | — | 1 | - |
| CHEMBL204048 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL100570 | — | Ki | = | 46.7 | nM | 7.33 |
| CHEMBL204495 | — | Ki | > | 2128.0 | nM | - |
| CHEMBL203972 | — | Ki | > | 2128.0 | nM | - |
| CHEMBL379469 | — | Ki | > | 2128.0 | nM | - |
| CHEMBL203160 | — | Ki | > | 2128.0 | nM | - |
| CHEMBL204549 | — | Ki | > | 2128.0 | nM | - |
| CHEMBL204048 | — | Ki | > | 2128.0 | nM | - |