Assay Detail
Binding
CHEMBL862610
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potency against Cathepsin S in Ramos cells by whole cell enzyme occupancy assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Ramos |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Identification of a potent and selective non-basic cathepsin K inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.59 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL195454 | — | — | 1 | 8.15 |
| CHEMBL437501 | — | — | 1 | 7.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL195454 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL437501 | — | IC50 | = | 95.0 | nM | 7.02 |