Assay Detail
Binding
CHEMBL862782
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to MMP1
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Matrix metalloproteinase target family landscape: a chemometrical approach to ligand selectivity based on protein binding site analysis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.25 | 7.52 |
| Ki | 1 | 5.60 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200274 | — | — | 1 | 7.52 |
| CHEMBL104022 | — | — | 1 | 6.98 |
| CHEMBL381189 | — | — | 1 | 5.60 |
| CHEMBL199917 | — | — | 1 | - |
| CHEMBL373261 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200274 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL104022 | — | IC50 | = | 104.0 | nM | 6.98 |
| CHEMBL381189 | — | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL199917 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL373261 | — | IC50 | > | 10000.0 | nM | - |