Assay Detail
Functional
CHEMBL863385
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of deltorphin-II from delta opioid receptor in mouse vas deferens
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New series of potent delta-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 9.85 | 10.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL380590 | — | — | 1 | 10.40 |
| CHEMBL198909 | — | — | 1 | 10.30 |
| CHEMBL372130 | — | — | 1 | 10.20 |
| CHEMBL571492 | — | — | 1 | 8.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL380590 | — | Kd | = | 0.03981 | nM | 10.40 |
| CHEMBL198909 | — | Kd | = | 0.05012 | nM | 10.30 |
| CHEMBL372130 | — | Kd | = | 0.0631 | nM | 10.20 |
| CHEMBL571492 | — | Kd | = | 3.162 | nM | 8.50 |