Assay Detail
Functional
CHEMBL863386
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonistic activity against mu opioid receptor in guinea-pig ileum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New series of potent delta-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.43 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL380590 | — | — | 1 | 5.80 |
| CHEMBL198909 | — | — | 1 | 5.26 |
| CHEMBL372130 | — | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL380590 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL198909 | — | IC50 | = | 5550.0 | nM | 5.26 |
| CHEMBL372130 | — | IC50 | = | 5900.0 | nM | 5.23 |