Assay Detail
Functional
CHEMBL863445
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Antiviral activity against Vaccinia virus in HFF cells
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vaccinia virus |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.40 | 5.47 |
| EC90 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200935 | DEAZANEPLANOCIN A | — | 2 | 5.47 |
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200935 | DEAZANEPLANOCIN A | EC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL5314375 | CIDOFOVIR | EC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL200935 | DEAZANEPLANOCIN A | EC90 | = | 21.5 | uM | - |