Assay Detail
Binding
CHEMBL863518
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Inhibitory activity against GSK3 from porcine brain
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 5.52 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL202935 | — | — | 1 | 6.34 |
| CHEMBL421087 | — | — | 1 | 4.70 |
| CHEMBL378359 | — | — | 1 | - |
| CHEMBL383097 | — | — | 1 | - |
| CHEMBL201382 | — | — | 1 | - |
| CHEMBL201418 | — | — | 1 | - |
| CHEMBL201114 | — | — | 1 | - |
| CHEMBL202979 | — | — | 1 | - |
| CHEMBL382056 | — | — | 1 | - |
| CHEMBL197700 | — | — | 1 | - |
| CHEMBL382906 | — | — | 1 | - |
| CHEMBL380656 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL202935 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL421087 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL378359 | — | IC50 | - | — | - | |
| CHEMBL383097 | — | IC50 | - | — | - | |
| CHEMBL201382 | — | IC50 | - | — | - | |
| CHEMBL201418 | — | IC50 | - | — | - | |
| CHEMBL201114 | — | IC50 | - | — | - | |
| CHEMBL202979 | — | IC50 | - | — | - | |
| CHEMBL382056 | — | IC50 | - | — | - | |
| CHEMBL197700 | — | IC50 | - | — | - | |
| CHEMBL382906 | — | IC50 | - | — | - | |
| CHEMBL380656 | — | IC50 | - | — | - |