Assay Detail
Functional
CHEMBL863564
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at adrenergic Alpha-2C receptor expressed in rat-mouse hybrid NH108-15 cell by adenylyl cyclase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | NH108-15 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.13 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL437314 | — | — | 1 | 5.25 |
| CHEMBL371300 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL437314 | — | EC50 | = | 5660.0 | nM | 5.25 |
| CHEMBL371300 | — | EC50 | = | 10000.0 | nM | 5.00 |