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Assay Detail

CHEMBL863697

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Trypanosoma brucei class1 Aldolase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma brucei
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Fructose-bisphosphate aldolase, glycosomal (CHEMBL4916)
Type SINGLE PROTEIN
Organism Trypanosoma brucei brucei

Publication

Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei.
Dax C, Duffieux F, Chabot N, Coincon M, Sygusch J, Michels PA, Blonski C.
J Med Chem (2006) 49 : 1499 -1502
PubMed 16509566 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.64 4.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL382634 1 4.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL382634 Ki = 23030.0 nM 4.64