Assay Detail
Functional
CHEMBL864392
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Dexamethasone induced GR transactivation of MMTV luciferase in HeLa cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery and SAR study of novel dihydroquinoline containing glucocorticoid receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.97 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL379024 | — | — | 1 | 7.35 |
| CHEMBL380646 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL379024 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL380646 | — | IC50 | = | 260.0 | nM | 6.58 |