Assay Detail

CHEMBL865154

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Functional

Inhibition of human lymphoma SUD4 cell viability

ChEMBL ↗

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Target

SUD4 (CHEMBL613711) ↗

Open DB target context

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SUD4 (CHEMBL613711) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target SUD4

CHEMBL613711

Anchored from Assay target.

Protein identity SUD4

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	SUD4
Confidence	1 — Organism
Curated By	Expert

Target

SUD4 (CHEMBL613711) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Aromatic sulfide inhibitors of histone deacetylase based on arylsulfinyl-2,4-hexadienoic acid hydroxyamides.

Marson CM, Savy P, Rioja AS, Mahadevan T, Mikol C, Veerupillai A, Nsubuga E, Chahwan A, Joel SP.
J Med Chem (2006) 49 : 800 -805
PubMed 16420064 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.12	5.12

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL198350	—	—	1	5.12

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL198350	—	IC50	=	7500.0	nM	5.12