Assay Detail
Binding
CHEMBL865883
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against LAR protein tyrosine phosphatase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Receptor-type tyrosine-protein phosphatase F (CHEMBL3521) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.19 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200117 | — | — | 1 | 6.16 |
| CHEMBL201662 | — | — | 1 | 4.21 |
| CHEMBL202197 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200117 | — | IC50 | = | 690.0 | nM | 6.16 |
| CHEMBL201662 | — | IC50 | = | 61700.0 | nM | 4.21 |
| CHEMBL202197 | — | IC50 | > | 10000.0 | nM | - |