Assay Detail
Functional
CHEMBL866021
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Cytotoxicity against mouse NIH3T3 cell line by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.89 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL214002 | — | — | 1 | 4.89 |
| CHEMBL378530 | — | — | 1 | - |
| CHEMBL212315 | — | — | 1 | - |
| CHEMBL377411 | — | — | 1 | - |
| CHEMBL212414 | — | — | 1 | - |
| CHEMBL211163 | — | — | 1 | - |
| CHEMBL426146 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL214002 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL378530 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL212315 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL377411 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL212414 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL211163 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL426146 | — | IC50 | > | 20000.0 | nM | - |