Assay Detail
Binding
CHEMBL866171
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Inhibition of testis ACE C domain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and molecular modeling of a lisinopril-tryptophan analogue inhibitor of angiotensin I-converting enzyme.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.68 | 7.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1237 | LISINOPRIL ANHYDROUS | 4.0 | 1 | 7.29 |
| CHEMBL212710 | — | — | 1 | 5.16 |
| CHEMBL212711 | — | — | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1237 | LISINOPRIL ANHYDROUS | Ki | = | 51.0 | nM | 7.29 |
| CHEMBL212710 | — | Ki | = | 7000.0 | nM | 5.16 |
| CHEMBL212711 | — | Ki | = | 26300.0 | nM | 4.58 |