Assay Detail
Functional
CHEMBL866406
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Inhibitory activity against Candida albicans
18
Total Activities
18
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel endoperoxides: synthesis and activity against Candida species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 18 | 4.34 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL52476 | — | — | 1 | 5.02 |
| CHEMBL54899 | — | — | 1 | 4.00 |
| CHEMBL293578 | — | — | 1 | 4.00 |
| CHEMBL157101 | KETOCONAZOLE | 4.0 | 1 | - |
| CHEMBL52664 | — | — | 1 | - |
| CHEMBL301338 | — | — | 1 | - |
| CHEMBL299505 | — | — | 1 | - |
| CHEMBL301376 | — | — | 1 | - |
| CHEMBL53708 | — | — | 1 | - |
| CHEMBL52831 | — | — | 1 | - |
| CHEMBL267345 | AMPHOTERICIN B | 4.0 | 1 | - |
| CHEMBL55396 | — | — | 1 | - |
| CHEMBL299577 | — | — | 1 | - |
| CHEMBL52248 | — | — | 1 | - |
| CHEMBL50573 | — | — | 1 | - |
| CHEMBL52634 | — | — | 1 | - |
| CHEMBL5465559 | NYSTATIN | 4.0 | 1 | - |
| CHEMBL53235 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL52476 | — | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL54899 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL293578 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL157101 | KETOCONAZOLE | IC50 | = | 250000.0 | nM | - |
| CHEMBL52664 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL301338 | — | IC50 | = | 500000.0 | nM | - |
| CHEMBL299505 | — | IC50 | = | 500000.0 | nM | - |
| CHEMBL301376 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL53708 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL52831 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL267345 | AMPHOTERICIN B | IC50 | < | 500.0 | nM | - |
| CHEMBL55396 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL299577 | — | IC50 | = | 125000.0 | nM | - |
| CHEMBL52248 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL50573 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL52634 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL5465559 | NYSTATIN | IC50 | = | 250000.0 | nM | - |
| CHEMBL53235 | — | IC50 | = | 125000.0 | nM | - |