Assay Detail
Binding
CHEMBL866564
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Inhibition of DPP4 by continuous fluorimetric assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.08 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL425584 | — | — | 1 | 6.39 |
| CHEMBL382127 | — | — | 1 | 4.52 |
| CHEMBL382382 | — | — | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL425584 | — | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL382127 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL382382 | — | IC50 | = | 46000.0 | nM | 4.34 |