Assay Detail
Functional
CHEMBL866926
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Antiviral activity against vaccinia virus in HFF cells by cytopathogenic effect assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vaccinia virus |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Toward orthopoxvirus countermeasures: a novel heteromorphic nucleoside of unusual structure.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.86 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL209889 | — | — | 1 | 6.22 |
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL209889 | — | EC50 | = | 600.0 | nM | 6.22 |
| CHEMBL5314375 | CIDOFOVIR | EC50 | = | 3200.0 | nM | 5.50 |