Assay Detail
Binding
CHEMBL867332
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Binding affinity to rat adrenergic alpha2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Design and synthesis of selective alpha1B adrenoceptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.58 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL541129 | — | — | 1 | 6.85 |
| CHEMBL537651 | — | — | 1 | 6.45 |
| CHEMBL537428 | — | — | 1 | 6.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL541129 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL537651 | — | Ki | = | 355.0 | nM | 6.45 |
| CHEMBL537428 | — | Ki | = | 370.0 | nM | 6.43 |