Assay Detail
Functional
CHEMBL867507
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against Plasmodium falciparum NF54
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.09 | 8.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL85223 | — | — | 1 | 8.19 |
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 8.05 |
| CHEMBL85891 | — | — | 1 | 8.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL85223 | — | IC50 | = | 6.5 | nM | 8.19 |
| CHEMBL269671 | ARTEMISININ | IC50 | = | 8.9 | nM | 8.05 |
| CHEMBL85891 | — | IC50 | = | 9.4 | nM | 8.03 |