Assay Detail
Functional
CHEMBL867571
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Antiviral activity against mutant HIV1 (V32I, M46I, V82A) infected MT4 cells by colorimetric XTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.88 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL197500 | — | — | 1 | 6.05 |
| CHEMBL436755 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL197500 | — | EC50 | = | 900.0 | nM | 6.05 |
| CHEMBL436755 | — | EC50 | = | 2000.0 | nM | 5.70 |