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Assay Detail

CHEMBL867575

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against class I FBP aldolase from rabbit
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Fructose-bisphosphate aldolase A (CHEMBL4695)
Type SINGLE PROTEIN
Organism Oryctolagus cuniculus

Publication

N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase.
Gavalda S, Braga R, Dax C, Vigroux A, Blonski C.
Bioorg Med Chem Lett (2005) 15 : 5375 -5377
PubMed 16236509 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 6 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE 1 6.00
CHEMBL196442 1 -
CHEMBL370845 1 -
CHEMBL197860 1 -
CHEMBL202288 1 -
CHEMBL199843 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE Ki = 1000.0 nM 6.00
CHEMBL196442 Ki > 1000000.0 nM -
CHEMBL370845 Ki > 10000000.0 nM -
CHEMBL197860 Ki > 10000000.0 nM -
CHEMBL202288 Ki > 10000000.0 nM -
CHEMBL199843 Ki > 10000000.0 nM -