Assay Detail
Binding
CHEMBL867772
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Inhibition of jack beans alpha-mannosidase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Canavalia ensiformis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.35 | 4.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL84844 | DEOXYMANNOJIRIMYCIN | — | 1 | 4.75 |
| CHEMBL207481 | — | — | 1 | 4.19 |
| CHEMBL206357 | — | — | 1 | 4.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL84844 | DEOXYMANNOJIRIMYCIN | Ki | = | 18000.0 | nM | 4.75 |
| CHEMBL207481 | — | Ki | = | 65000.0 | nM | 4.19 |
| CHEMBL206357 | — | Ki | = | 78000.0 | nM | 4.11 |